A Case of IgA kappa Light Chain Deposition Disease and Combined Adult Fanconi Syndrome with Auer rod-like Intracytoplasmic Inclusions in Plasma Cells and Proximal Renal Tubular Cells / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 248-252, 2007.
Article
in Korean
| WPRIM
| ID: wpr-7857
ABSTRACT
We report a case of IgA kappa light chain deposition disease and combined adult Fanconi syndrome with Auer rod-like intracytoplasmic inclusions in plasma cells and proximal renal tubular cells in a 54-yr-old female. Cytochemical stainings revealed a strong acid phosphatase activity of the inclusions and weak periodic acid-Schiff positivity, whereas the reactions for peroxidase and alpha-naphthyl acetate esterase were negative. An immunostaining verified IgA-kappa inside the plasma cells. Kidney biopsy revealed Bence Jones cast nephropathy with kappa light chain positivity, and Congo red staining was negative. Electron microscopy showed needle-shaped crystals located in tubular epithelial cells.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Paraproteinemias
/
Plasma Cells
/
Immunoglobulin A
/
Inclusion Bodies
/
Immunoglobulin kappa-Chains
/
Fanconi Syndrome
/
Kidney Tubules, Proximal
Limits:
Female
/
Humans
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2007
Type:
Article
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