A Case of Hunter Syndrome / 대한피부과학회지
Korean Journal of Dermatology
;
: 928-932, 2008.
Article
in Korean
| WPRIM
| ID: wpr-78584
ABSTRACT
We report a case of Hunter syndrome in a 4 year old boy, who presented with firm skin colored papules and nodules that coalesce to form a reticular pattern (pebbling of the skin) with extensive Mongolian spots. The lesions are arranged bilaterally and symmetrically over the scapulae, upper arm and lateral aspects of the thighs. He also has low intelligence, coarse face, saddle nose and claw hand contracture of both hands. The result of qualitative analysis of urine was positive for dermatan sulfate and heparan sulfate. And enzyme activity of iduronate-2-sulfatase is decreased in plasma and leukocyte. A skin biopsy specimen section stained with hematoxylin-eosin showed widely separated collagen bundles in the dermis associated with mucin deposition.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arm
/
Plasma
/
Scapula
/
Skin
/
Thigh
/
Biopsy
/
Nose
/
Collagen
/
Mucopolysaccharidosis II
/
Contracture
Type of study:
Qualitative research
Limits:
Animals
Language:
Korean
Journal:
Korean Journal of Dermatology
Year:
2008
Type:
Article
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