Drug-induced nephrotoxicity
Journal of the Korean Medical Association
;
: 30-35, 2020.
Article
in Korean
| WPRIM
| ID: wpr-786180
ABSTRACT
Drugs are a common cause of acute and chronic kidney disease and contribute to patient morbidity and increased healthcare utilization. Drug-induced nephrotoxicity is approximately 14% to 26% in adults and tends to increase among certain patients and/or with complex clinical conditions. Unfortunately, apart from conservative management, including drug withdrawal, no effective treatment is known for this condition. Therefore, in order to reduce the frequency of drug-induced nephrotoxicity, early recognition of renal toxicity and appropriate prevention strategies, such as understanding the exact mechanisms of renal injury, patient and drug-related risk factors, and preemptive measures are needed. In this review, we will present the mechanisms of drug-induced nephrotoxicity and general preventive strategies for clinical physicians.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pharmaceutical Preparations
/
Risk Factors
/
Delivery of Health Care
/
Renal Insufficiency
/
Renal Insufficiency, Chronic
/
Kidney Tubules
Type of study:
Etiology study
/
Risk factors
Limits:
Adult
/
Humans
Language:
Korean
Journal:
Journal of the Korean Medical Association
Year:
2020
Type:
Article
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