Clinical features and outcomes in kidney transplant recipients with renal cell carcinoma: a single-center study
Kidney Research and Clinical Practice
;
: 517-524, 2019.
Article
in English
| WPRIM
| ID: wpr-786194
ABSTRACT
BACKGROUND:
Previous studies have recommended a 2- to 5-year waiting time prior to kidney transplantation (KT) in patients with end-stage renal disease (ESRD) and symptomatic renal cell carcinoma (RCC) and no delay for incidental early-stage RCC. Data on Asian KT recipients are unavailable.METHODS:
This is a Korean single-center retrospective study on 35 KT recipients with ESRD and RCC. Patients were classified into two groups early KT (KT performed within 1 year after nephrectomy for RCC, including KT with simultaneous nephrectomy) and delayed KT (KT performed over than 1 year after nephrectomy for RCC). Patient survival, graft survival, and cancer recurrence were compared between both groups.RESULTS:
There were no statistically significant differences in patient survival (P = 0.388), graft survival (P = 0.317), or graft rejection rate (P = 0.207) between the early and delayed KT groups. Additionally, there were no differences in pathological characteristics or RCC stage other than cancer histology acquired cystic disease-associated RCC (47.4%) was the most common RCC type in the early KT group, whereas clear cell type (62.5%) was the most common RCC type in the delayed KT group. No RCC recurrence was observed.CONCLUSION:
Patients with early-stage and asymptomatic RCC do not require a mandatory observational period prior to KT after curative nephrectomy
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Recurrence
/
Carcinoma, Renal Cell
/
Retrospective Studies
/
Kidney Transplantation
/
Asian People
/
Transplant Recipients
/
Graft Rejection
/
Graft Survival
/
Kidney
/
Kidney Failure, Chronic
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Kidney Research and Clinical Practice
Year:
2019
Type:
Article
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