Composite Cutaneous Lymphoma (Iatrogenic Immunodeficiency-Associated Lymphoproliferative Disorder) in a Patient with Rheumatoid Arthritis Treated with Methotrexate: Staging and Evaluation of Response to Therapy with ¹⁸F-FDG PET/CT / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 261-265, 2017.
Article
in English
| WPRIM
| ID: wpr-786931
ABSTRACT
A 67 year old woman with a 10 year history of rheumatoid arthritis (RA) treated with methotrexate and prednisone, presented with a 2 year history of worsening multiple cutaneous plaques of variable appearance. Two distinct skin lesions were biopsied to reveal a composite cutaneous lymphoma, possibly caused by long term methotrexate therapy. An [18F] fluoro-2-deoxy-D-glucose (¹⁸F-FDG) positron emission tomography/computed tomography (PET/CT) was performed to stage the malignancy, and was later repeated to evaluate response to chemotherapy, which guided subsequent management. We present the PET/CT imaging findings of this very rare iatrogenic (methotrexate induced) immunodeficiency-associated lymphoproliferative disorder.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Arthritis, Rheumatoid
/
Skin
/
Prednisone
/
Methotrexate
/
Drug Therapy
/
Electrons
/
Composite Lymphoma
/
Positron Emission Tomography Computed Tomography
/
Lymphoma
/
Lymphoproliferative Disorders
Limits:
Female
/
Humans
Language:
English
Journal:
Korean Journal of Nuclear Medicine
Year:
2017
Type:
Article
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