Langerhans' Cell Histiocytosis Masquerading as Metastatic Papillary Thyroid Cancer on F-18 FDG PET/CT: Diagnostic Dilemma Solved by PET/CT-Guided Biopsy / 대한핵의학회잡지
Korean Journal of Nuclear Medicine
;
: 394-397, 2018.
Article
in English
| WPRIM
| ID: wpr-787007
ABSTRACT
We present a case of papillary thyroid cancer (post-thyroidectomy status) on regular treatment with suppressive Levothyroxine therapy. On follow-up at 6 months after radioactive iodine ablation for remnant thyroid tissue, her thyroglobulin, and anti-thyroglobulin levels were 0.06 ng/ml and 670 IU/ml, respectively. Low-dose whole-body I-131 scan was negative. To look for the cause of isolated increased anti-thyroglobulin level, a whole-body ¹⁸F-FDG PET/CT was done which revealed multiple FDG-avid lytic skeletal lesions suggestive of metastases. For confirmation of diagnosis, ¹⁸F-FDG PET/CT-guided metabolic biopsy was done, which revealed Langerhans' cell histiocytosis on histopathological examination.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thyroglobulin
/
Thyroid Gland
/
Thyroxine
/
Biopsy
/
Thyroid Neoplasms
/
Histiocytosis
/
Follow-Up Studies
/
Diagnosis
/
Positron Emission Tomography Computed Tomography
/
Iodine
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
Language:
English
Journal:
Korean Journal of Nuclear Medicine
Year:
2018
Type:
Article
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