Correlation between meteorological factors and short-term outcomes in patients with noncardioembolic stroke / 国际脑血管病杂志

ABSTRACT

Objective To investigate the correlation between meteorological factors and short-term outcomes in patients with acute noncardioembolic stroke.Methods Patients with acute noncardioembotic stroke admitted to the Department of Neurology,the Second Hospital of Tianjin Medical University from March 2009 to February 2012,were enrolled retrospectively.The modified Rankin Scale (mRS) scores were collected at discharge or 14 d after onset,and good outcome was defined as mRS 0-2,poor outcome as mRS ＞ 2.The demographic,baseline clinical data,laboratory findings,and meteorological parameters on the day of onset were compared between the good outcome group and the poor outcome group.Multivariate logistic regression analysis was used to determine the independent risk factors of short-term outcomes.Results A total of 868 patients w ith acute noncardioembolic stroke w ere enrolled,including 535 (61.6％) with good outcome and 333 (38.4％) with poor outcome.Univariate analysis showed that age,baseline National Institutes of Health Stroke Scale score,systolic pressure,fasting blood glucose,daily average wind speed as w ell as the proportion of ischemic heart disease,history of stroke or transient ischemic attack,and moderate to severe stroke in the poor outcome group were significantly higher than those in the good outcome group;daily average temperature and daily average relative humidity in the poor outcome group w ere significantly low er than those in the good outcome group (all P ＜ 0.05).Multivariate logistic regression analysis showed that lower daily average temperature (odds ratio 0.978,95％ confidence interval 0.959-0.998;P =0.032) and higher daily average wind speed (odds ratio 1.442,95％ confidence interval 1.065-1.953;P =0.018) w ere independently correlated with the short-term outcomes.Conclusion Daily average temperature and daily average wind speed were significantly correlated with the short-term outcomes in patients with acute noncardioembolic stroke.