Influence of metabolic syndrome on carotid intima-media thickness in young and middle-aged pa- tients with essential hypertension / 上海预防医学

ABSTRACT

Objective] To evaluate the influence of metabolic syndrome ( MS) on carotid intima-media thickness ( IMT) in essential hypertension ( EH) . [ Methods] A total of 168 young and middle-aged EH patients were divided into MS group (88 cases) and non-MS group (80 cases).Between the two groups were measured and compared IMT , body mass index ( BMI ) , waist circumference ( WC ) , systolic blood pressure ( SBP ) , diastolic blood pressure ( DBP ) , fasting plasma glucose ( FPG ) , total cholesterol (TC),triglyceride (TG),high-density lipoprotein (HDL-C),low-density lipoprotein (LDL-C) and others. [ Results] Comparison between MS group and non-MS group showed that the level of BMI , FPG, WC, TC, TG, LDL-C and IMT were higher in MS group,P all <0.05.Multiple Logistic regression analysis showed that age,SBP,FPG and LDL-C were the related factors for carotid IMT. [Conclusion] MS is associated with carotid IMT in young and middle-aged patients with EH .MS and EH may jointly participate in the process of atherosclerosis .Apart from control of blood pressure , correction of metabolic disorders is also necessary in order to prevent complication of atherosclerosis .