Study on hemorheological changes of carbon tetrachloride(CCl4)induced hepatic fibrosis in rat / 药学实践杂志
Journal of Pharmaceutical Practice
;
(6): 78-79, 2001.
Article
in Chinese
| WPRIM
| ID: wpr-790298
ABSTRACT
OBJECTIVE:To study the hemorheological paramenters in rat with hepatic fibrosis. METHODS:
Hepatic fibrosis in rat was induced by CCl4 treatment. Whole blood viscosity, plasma viscosity, Hematocrit(Hct) and dynamic parameters of red blood cell(RBC) were investigated.RESULTS:
As compared with the normal group, the hemorheological parameters such as whole blood viscosity, plasma viscosity, Hematocrit(Hct), RBC's aggregation and rigidity were increased obviously.CONCLUSION:
High blood vicosity and low RBC's deformation ability can lead to blood circulation obstacle, thus will aggravate hepatic fibrosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Pharmaceutical Practice
Year:
2001
Type:
Article
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