Detection of glinides adulterated in traditional Chinese medicine for diabetes by TLC-SERS / 药学实践杂志
Journal of Pharmaceutical Practice
;
(6): 206-208,230, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-790315
ABSTRACT
Objective To establish detection method of glinides adulterated illegally in hypoglycemic traditional Chinese medi -cine (TCM) by surface enhanced Raman spectroscopy (SERS).Methods Adulterated chemicals and TCM matrixes were separated by TLC first.Then trace substances in TLC plate was tested by SERS method .By investigating SERS detection conditions of glinides chemi-cals in simulated positive samples , a detection method was established to detect illegal adulterant in hypoglycemic TCM .Results Better SERS spectra of glinides could be obtained by silver sol prepared with organic solvent DMF .Conclusion The detection method coupled with TLC and SERS in this paper was simple , fast and economical which could be used to detect glinides adulterated illegally in hypogly -cemic Chinese patent medicine quickly .
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Journal of Pharmaceutical Practice
Year:
2014
Type:
Article
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