Lox-1, a new target in cardiovascular disease / 药学实践杂志

ABSTRACT

Objective Lox-1 ( lectin-like oxidized low-density lipoprotein receptor-1 ) was one of the main receptor of ox-LDL, which took an important role in vascular endothelial dysfunction , the formation of foam cells , and the stability of atherosclerotic plaques .To investigate the role of Lox-1 in cardiovascular diseases .Methods The literatures of Lox-1 in cardiovascular diseases retro-spectively were reviewed .Results As a new ox-LDL scavenger receptor , Lox-1 played an important role in cardiovascular diseases . Conclusion Lox-1 might provide new ideas for cardiovascular diseases .