Quality of control of compound chlorhexidine acetate ointment / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 258-260,266, 2016.
Article
in Zh
| WPRIM
| ID: wpr-790605
Responsible library:
WPRO
ABSTRACT
Objective To improve the standard of the quality control of compound chlorhexidine acetate ointment . Methods TLC was used to control the quality of menthol crystal and camphor .A method to determine chlorhexidine acetate and cocaine hydrochloride simultaneously by HPLC was established .Results The spots of menthol crystal and camphor in TLC were clear .Chlorhexidine acetate and cocaine hydrochloride showed excellent linearity ,which were at the range of 10.01-160.14 μg/ml and 10 .01-160 .14 μg/ml ,respectively .The average recoveries were 101 .5% (RSD=1 .8% ) and 100 .5% (RSD=2 .8% ) .Conclusion The methods were simple ,sensitive and with good reproducibility and could be used to control the quality of compound chlorhexidine acetate ointment .
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WPRIM
Language:
Zh
Journal:
Journal of Pharmaceutical Practice
Year:
2016
Type:
Article