Cost-effectiveness analysis of Danshenchuanxiongqin injection vs salvianolate injection for angina pectoris / 药学实践杂志

ABSTRACT

Objective To compare the cost-effectiveness of Danshenchuanxiongqin injection versus salvianolate injection for angina pectoris.Methods Databases including CBM,CNKI,VIP,Cochrane library,Pubmed,Embase and Wanfang were electronically searched for the randomized controlled trials(RCTs)on the comparison between Danshen Chuanxiongqin injection and Dsnshenduofensuanyan injection.Literatures were screened and data were extracted in accordance with the inclusion and exclusion criteria.Clinical efficacy of the two drugs were obtained through indirect Meta-analysis.Economic evaluation was carried out using the cost-effectiveness analysis,direct medical cost data included the cost of conventional treatment,drug,ex-amination and hospital expenses.Results Through indirect Meta-analysis,the improvement efficiency of angina were 89.51%and 92.52% for Danshenchuanxiongqin injection and salvianolate injection.The success rates of ECG were 81.40% and 84·05% for two drugs. The costs of Danshenchuanxiognqin injection and salvianolate injection were 4 099.71 and 5 410.16 CNY.The Cost-effectiveness ratio of angina improve of two drugs were 45.80 and 58.48,while the ECG improve were 50.36 and 64.37.And the sensitivity analysis results were stable.Conclusion Compared to salvianolate injection,salvi-anolate injection was probably cost-effective for angina pectoris.