Progress of human CCAAT/enhancer binding protein epsilon on inflammation and infection / 中华危重病急救医学
Chinese Critical Care Medicine
;
(12): 1420-1422, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-791093
ABSTRACT
Inflammation and infection are main causes of death in critically ill patients. But traditional treatment are non-comprehensive and limited. Human CCAAT/enhancer binding protein epsilon (C/EBPε) is a key transcription factor regulating the terminal differentiation of neutrophils. It plays an important role in anti-inflammatory and anti-infective process by regulating inflammatory response cells. This article reviews the changes of C/EBPε in inflammation and infection, related regulatory mechanisms and targeted reversal measures, in order to provide references for exploring new directions and effective measures for inflammation and infection treatment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Critical Care Medicine
Year:
2019
Type:
Article
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