The influence of cognition on suicidal ideation of major depressive patients / 中华行为医学与脑科学杂志

ABSTRACT

Objective To analyze the influence of cognition on suicidal ideation in patients with major depressive disorder. Methods A total of 108 inpatients with major depressive disorder from January 2017 to September 2018 in Beijing Huilongguan Hospital were enrolled. They were divided into suicidal idea- tion group ( n=42) and non-suicidal ideation group ( n= 66) by the self-rating idea of suicide scale (SIOSS). Cognition was assessed by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS). The general situation was assessed by self-made general situation questionnaire. The related fac-tors were analyzed by Logistic regression. Results (1) The rate of suicidal ideation was 44. 4% in patients with major depressive disorder. (2) The total score of RBANS and five-factor scores of RBANS in suicidal i-deation group were lower than those in non-suicidal ideation group(total RBANS score(63. 0±7. 9) vs (73. 8 ±7. 7);immediate memory(62. 7± 8. 8) vs ( 70. 8± 7. 6);visual span( 67. 2± 10. 0) vs ( 72. 7± 9. 8);speech function(83. 3±13. 8) vs (91. 5±4. 5);attention(85. 3±11. 9) vs (99. 9±8. 5);delayed memory(53. 5±7. 7) vs (62. 3±9. 7),F=6. 335-46. 660,P<0. 05). (3) Logistic regression showed,years of educa-tion were risk factors for suicidal ideation ( β=0. 289, P=0. 013, OR=1. 335,95% CI=1. 063-1. 676), RBANS attention factor(β=-0. 161,P=0. 000,OR=0. 851,95%CI=0. 778-0. 931) and RBANS delayed memory factor score(β=-0. 151,P=0. 006,OR=0. 860,95%CI=0. 772-0. 957) were protective factors for suicidal ideation. Conclusion Cognitive function has an impact on suicide ideation of depressive patients, mainly attention and delayed memory are protective factors for suicide ideation.