Determination and analysis of allergen specific IgE in 1 028 children with allergic dermatosis / 中国医师杂志

ABSTRACT

Objective To observe the differences in specific IgE of allergic diseases.Methods The allergens in 1 028 patients (including 606 cases of eczema/specific dermatitis,319 Cases of urticaria,103 cases of papular urticaria and prurigo) were detected by German Allergy Screen Immune mark method.Results There were statistically significant differences (P ＜ 0.05) in the positive rate of allergens among the four allergic diseases,including Penicillium notatum/ Piptocephalis/ aspergillus fumigatus/aspergillus niger/Alternaria (x2 =6.663),milk (x2 =10.320) and cashew nut (x2 =14.325);The common allergen in ＜ 1-year-old group was cat dander (22.75％),egg white (35.93％);The common allergen in 1 to 3 years old group was dog dander (22.17％),milk (61.82％) and crab (3.45％).The common allergen in ＞ 3-year-old group was dust mite (10.77％),cockroach (3.52％),Penicillium notatum/Piptocephalis/aspergillus fumigatus/aspergillus niger/Altemaria (21.32％),Short ragweed/artemisia/Humulus scandens/quinoa (14.73％).The positive rate of specific IgE against house dust in the third quarter was the highest (17.78％) and the difference was statistically significant (x2 =14.443,P =0.002).Among the statistically significant difference in the positive rate of specific IgE between eczema/atopic dermatitis in different age groups (x2 =10.204,P =0.006),the positive rate in the group of 1 to 3 years was the highest.Conclusions Different diseases,ages,and seasonal specific allergens are different,individualized treatment can be carried out according to disease types,ages and seasons.