Your browser doesn't support javascript.
loading
Measurement of residual radioactivity in postoperative inpatients with differentiated thyroid carcinoma after 131 I treatment using robot / 中华核医学与分子影像杂志
Chinese Journal of Nuclear Medicine and Molecular Imaging ; (6): 601-605, 2019.
Article in Chinese | WPRIM | ID: wpr-791568
ABSTRACT
Objective To evaluate the residual radioactivity after 131 I treatment in postoperative in-patients with differentiated thyroid carcinoma ( DTC) using service robot in nuclear medicine ward, and as-sess the time for patients to be released from isolation. Methods From September 2017 to June 2018, 297 patients ( 94 males, 203 females, age19-80 years) with DTC who underwent 131 I treatment after surgery were included. According to the purpose of treatment and the prescription dosage of 131 I, patients were divid-ed into 8 groups4 groups accepted 131 I remnant ablation therapy ( RAT) with different dosages, which were 3700 MBq ( RAT1, n=34) , 4440 MBq ( RAT2, n=122) , 5550 MBq ( RAT3, n=81) and 7400 MBq ( RAT4, n=27) , respectively;4 groups had 131 I treatment for recurrent/metastatic lesions ( RMLT) , and the dosages were 3700 MBq ( n=1) , 4440 MBq ( n=2) , 5550 MBq ( n=14) and 7400 MBq ( n=16) . At 4, 24, 48 and 72 h after 131 I administration, the dose equivalent rates at 2 cm away from the patient's neck and at 1 m away from the body were measured by the robot designed for nuclear medicine ward. Kruskal-Wallis rank sum test and Mann-Whitney U test were used to analyze the data. Results Neck dose equivalent rates for patients with RAT at different time points ( 4, 24, 48 and 72 h) after 131 I administration were significantly different among 4 groups (H values20.889-46.410, all P<0.05), as well as the body dose equivalent rates (H values27.181-35.497, all P<0.05). The neck dose equivalent rates at 24, 48 and 72 h after 131 I administration were statistically different between group 3 and 4 for patients with RMLT ( z values2.328-3.076, all P<0.05;data in group 1 and 2 were too limited to be compared) , while there was no statistical difference for the body dose equivalent rates (z values0.333-1.621, all P>0.05). The radioactivity retention in patients decreased rapidly within 24 h, then slowed down gradually and became ex-tremely low at 72 h. At 72 h after 131I administration, 96.6%(255/264) patients with RAT and 100%(33/33) patients with RMLT were lower than 23.3 μSv/h, which meant the patients could be discharged from hospitalization. Conclusions Nuclear medicine ward service robots may dynamically measure residual radi-oactivity in DTC patients who take 131 I treatment, providing individualized isolation solutions.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Nuclear Medicine and Molecular Imaging Year: 2019 Type: Article

Similar

MEDLINE

...
LILACS

LIS

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Nuclear Medicine and Molecular Imaging Year: 2019 Type: Article