Pulmonary Mucormycosis Treated Successfully with Posaconazole as Salvage Therapy / 계명의대학술지
Keimyung Medical Journal
; : 127-132, 2015.
Article
in En
| WPRIM
| ID: wpr-79178
Responsible library:
WPRO
ABSTRACT
Mucormycosis (formerly known as zygomycosis) is a life-threatening opportunistic mycosis that infects a broad range of hosts with qualitative or quantitative defects in innate immunity. The overall mortality rate of pulmonary mucormycosis is above 70%. The prognosis and outcome of pulmonary mucormycosis have not improved significantly over the last decade, mainly because of difficulty in early diagnosis and the limited activity of current antifungal agents against members of the order Mucorales. We report a case of pulmonary mucormycosis treated successfully with posaconazole as salvage therapy. We suggest that posaconazole may be considered as an alternative therapeutic approach in patients with invasive pulmonary mucormycosis who are unable to tolerate surgical treatment.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Prognosis
/
Mortality
/
Salvage Therapy
/
Early Diagnosis
/
Immunity, Innate
/
Mucorales
/
Mucormycosis
/
Antifungal Agents
Type of study:
Diagnostic_studies
/
Prognostic_studies
/
Qualitative_research
/
Screening_studies
Limits:
Humans
Language:
En
Journal:
Keimyung Medical Journal
Year:
2015
Type:
Article