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Roles of innate lymphoid cells in tumor immunity and their clinical significance / 中华微生物学和免疫学杂志
Chinese Journal of Microbiology and Immunology ; (12): 715-719, 2019.
Article in Chinese | WPRIM | ID: wpr-792027
ABSTRACT
Innate lymphoid cells ( ILCs) are a recently characterized family of immune cells that have critical roles in innate immunity, immune regulation, maintenance of tissue homeostasis, and tissue re-pair and remodeling. Besides the conventional innate lymphocytes including NK cells and lymphoid tissue-in-ducer cells, the ILC family can be categorized into three groups, ILC1s, ILC2s and ILC3s. These non-cyto-toxic ILC subsets have been identified to confer a diverse array of functions in oncogenesis and metastasis, immune surveillance, and antitumor immunity. In this review, we summarized the emerging findings in re-cent years regarding the roles of ILCs in immuno-oncology, and highlighted their potentials in immunothera-peutic approaches to tumors.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Journal of Microbiology and Immunology Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study Language: Chinese Journal: Chinese Journal of Microbiology and Immunology Year: 2019 Type: Article