Prevalence and risk factors of hyperuricemia in physical examination group of Zhangjiakou / 预防医学

ABSTRACT

Objective To investigate the prevalence and risk factors of hyperuricemia in physical examination group of Zhangjiakou, and to provide evidence for the prevention of hyperuricemia. Methods The physical examination people in the Number One Hospital of Zhangjiakou were selected as the research objects from May 2016 to May 2017 . Their physique indexes such as height, weight and blood pressure were tested, and their blood sample were collected and biochemical indexes such as fasting plasma glucose (FPG), blood uric acid (UA), triglyceride (TG) and total cholesterol (TC) were detected. Logistic regression model were used to analyze the influencing factors of hyperuricemia. Results A total of 17273 examinees were recruited, with the average age of (47.42±14.28) years. There were 10324 men (59.77％) and 6949 women (40.23％) . The prevalence rate of hyperuricemia was 22.14％. The prevalence rate of hyperuricemia in men was 28.39％, higher than that of women (12.87％) (P<0.001) . Logistic regression analysis showed that obesity/overweight (OR=2.206, 95％ CI 1.986-2.450), high TG (OR=2.089, 95％CI 1.903-2.293) and high TC (OR=1.121, 95％CI 1.006-1.249) were risk factors of the male patients with hyperuricemia, while the elderly (OR=0.982, 95％CI 0.979-0.985) and high FPG (OR=0.657, 95％ CI 0.587-0.736) were protective factors. The risk factors of the female patients with hyperuricemia were the elderly (OR=1.008, 95％CI 1.001-1.014), obesity/overweight (OR=2.193, 95％CI 1.864-2.579), high FPG (OR=1.379, 95％CI 1.128-1.687) and high TG (OR=2.209, 95％ CI 1.879-2.597) . Conclusion The prevalence of hyperuricemia among residents in Zhangjiakou of Hebeiis high. Overweight / obesity and high TG are the risk factors for hyperuricemia.