Mycoplasma pneumoniae infection and drug resistance among children in Fuyang District / 预防医学
Journal of Preventive Medicine
;
(12): 257-259,265, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-792725
ABSTRACT
Objective In order to investigate the Mycoplasma pneumonia (MP) infection and drug resistance in children in Fuyang, Hangzhou, and to provide a rational basis for the clinical diagnosis and treatment of MP in children. Methods A total of 1104 respiratory tract samples were collected from children patients with pneumonia. MP and its mutations in 23S rRNA gene locus were detected by real-time PCR. Then analyze pertinence between the clinical data and experimental results were conducted. Results Among 1104 respiratory tract samples, 175 cases (15.85%) were MP positive. Moreover, the mutation of 23S rRNA gene locus existed in 115 MP positive samples with the positive infection rate of 65.71% . The infection rate (25.74%) and mutation rate (82.69%) in summer (Jul.-Sep.) was higher than other seasons, and the infection rate (11.72%) and mutation rate (40.63%) was the lowest in winter (Jan.-Mar.) . The infection rates of male and female children were 66.67% and 64.56%, and the mutation rates of male and female children were 66.67% and 64.56%. Conclusion MP infection may be related with climate and age. 23S rRNA gene locus mutation has a higher detection rate, prompting that MP shows high resistant rate to macrolides.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Preventive Medicine
Year:
2018
Type:
Article
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