Invasive Cribriform Carcinoma Arising in Malignant Phyllodes Tumor of Breast: A Case Report
Korean Journal of Pathology
;
: 205-209, 2012.
Article
in English
| WPRIM
| ID: wpr-79417
ABSTRACT
Phyllodes tumor is an uncommon fibroepithelial neoplasm of the breast. And it is characterized by expanded stroma with increased cellularity and elongated epithelium-lined clefts. Mammary carcinomas within phyllodes tumors have been rarely reported. To date, however, no reports have described the invasive cribriform carcinoma arising in malignant phyllodes tumor. Here, we report a 62-year-old woman who presented with a large breast mass. Microscopically, the mass was a typical malignant phyllodes tumor showing well developed leaf-like architecture and stromal overgrowth with high cellularity and nuclear pleomorphism. In a portion of the tumor, however, the epithelial component showed a cribriform pattern of proliferation in the absence of myoepithelial cells, suggestive of the invasive cribriform carcinoma. To our knowledge, this is rare and it is difficult to make a differential diagnosis of it. Here, we report our case with a review of literatures.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Breast
/
Adenocarcinoma
/
Neoplasms, Fibroepithelial
/
Phyllodes Tumor
/
Diagnosis, Differential
Type of study:
Diagnostic study
Limits:
Female
/
Humans
Language:
English
Journal:
Korean Journal of Pathology
Year:
2012
Type:
Article
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