Preoperative Localization in Primary Hyperparathyroidism: Comparison of Tc99m MIBI Scan and Tl201/Tc99m Subtraction Scan
Journal of the Korean Surgical Society
;
: 23-29, 2002.
Article
in Korean
| WPRIM
| ID: wpr-79493
ABSTRACT
PURPOSE:
Recently Tc99m MIBI (methoxyisobutylisonitrile) has been described as an alternative to thallium for localizing parathyroid lesions. The purpose of this study was to compare the efficacy of a Tc99m MIBI scan with a Tl201/Tc99m subtraction scan for localizing parathyroid lesions in patients with primary hyperparathyroidism.METHODS:
Among 31 cases of primary hyperparathyroidism operated on at the Department of Surgery, Seoul National University Hospital from January 1997 to June 2001, a Tl201/Tc99m subtraction scan was performed on 16 patients and a Tc99m MIBI scan on 22 patients. Seven patients underwent both.RESULTS:
The pathology was a single adenoma in 28 patients, a hyperplasia in 1 patient and a carcinoma in 2 patients. Hypercalcemia was controlled postoperatively in all cases. The sensitivities of the Tl201/Tc99m subtraction scan and Tc99m MIBI scan were 53.3% and 86.4%, respectively. The positive predictive values were 100% of the two study groups.CONCLUSION:
We concluded that the better accuracy, superior image quality and lower cost of Tc99m MIBI scan will make it the new radiopharmaceutical parathyroid scan of choice. A unilateral approach can be used with a high degree of success, as in case of a preoperatively localized single parathyroid adenoma, which was confirmed when surgical exploration identified of a normal ipsilateral gland.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Parathyroid Neoplasms
/
Pathology
/
Thallium
/
Adenoma
/
Hyperparathyroidism, Primary
/
Seoul
/
Hypercalcemia
/
Hyperplasia
Limits:
Humans
Country/Region as subject:
Asia
Language:
Korean
Journal:
Journal of the Korean Surgical Society
Year:
2002
Type:
Article
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