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Fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation / 中华血液学杂志
Chinese Journal of Hematology ; (12): 853-855, 2019.
Article in Chinese | WPRIM | ID: wpr-796976
ABSTRACT
Objective@#To explore the availability and safety of fecal microbiota transplantation for patients with refractory diarrhea after allogeneic hematopoietic stem cell transplantation (allo-HSCT) .@*Methods@#Four acute leukemia patients suffered from refractory diarrhea after allo-HSCT. One of them was refractory intestinal infection, the others were intestinal graft versus host disease. One or two doses of fecal microbiota, 3.4-6.0 U for one dose, were infused via nasal-jejunal tube. The curative effect and side effects were reviewed.@*Results@#Three cases achieved complete remission while 1 was stable disease. The side effects included fever, abdominal pain and diarrhea, which all were Ⅰ grade.@*Conclusion@#Fecal microbiota transplantation was effective and safe for refractory diarrhea after allo-HSCT.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Hematology Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Hematology Year: 2019 Type: Article