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Correlation and prognosis analysis of hypoalbuminemia in patients with heart failure with preserved ejection fraction / 中国医师进修杂志
Chinese Journal of Postgraduates of Medicine ; (36): 946-950, 2019.
Article in Chinese | WPRIM | ID: wpr-797113
ABSTRACT
Objective@#To investigate the correlation between hypoalbuminemia and heart failure with preserved ejection fraction (HFpEF) and to analyze the prognosis of patients with HFpEF and hypoalbuminemia.@*Methods@#Three hundred and fourteen patients with HFpEF who were hospitalized in Department of Cardiology, Shengjing Hospital of China Medical University from January 2012 to December 2013 were analyzed retrospectively. These patients were divided into two groups according to the serum albumin, hypoalbuminemia (< 35g/L) group and normal albumin group (≥ 35g/L). The prognostic correlation between hypoalbuminemia and HFpEF was analyzed by COX regression analysis.@*Results@#Patients with hypoalbuminemia had a higher mortality 20.2%(20/99) vs. 9.8%(21/215). There was no significant difference in the average hospitalization timehospital mortality and readmissions for heart failure between two groups. Univariate COX regression analysis showed that the relative risk ratio of readmissions between normal albumin group and hypoalbuminemia group was 0.554(0.374-0.820), and the relative risk ratio of cardiogenic death was 0.283(0.148-0.538), P < 0.05.@*Conclusions@#HFpEF patients with hypoalbuminemia have relative poor heart function; hypoalbuminemia may be a risk factor of cardiac death for patients with HFpEF.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Postgraduates of Medicine Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Prognostic study Language: Chinese Journal: Chinese Journal of Postgraduates of Medicine Year: 2019 Type: Article