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Clinical features and risk factors of 90 patients with diabetic foot recurrent infection / 中国基层医药
Chinese Journal of Primary Medicine and Pharmacy ; (12): 1217-1220, 2019.
Article in Chinese | WPRIM | ID: wpr-797129
ABSTRACT
Objective@#To investigate the clinical features and risk factors of diabetic foot recurrence infection in diabetes mellitus (DM) patients.@*Methods@#A total of 158 patients with diabetic foot infection from January 2014 to December 2017 admitted to the First Affiliated Hospital of Xiamen University were selected in the study.There were 90 patients with diabetic foot recurrence.The clinical data of patients with recurrent infection and non-recurrent infection were compared and analyzed.Multivariate logistic regression was used to analyze the risk factors associated with recurrent infection of diabetic foot.@*Results@#Ninety patients with recurrent infection of diabetic foot were cultured with 108 strains of pathogens, of which Gram-positive(G+ ), Gram-negative(G-), and other pathogens accounted for 54.63%(59 strains), 39.81%(43 strains), 5.56%(6 strains), respectively.The differences in disease duration, age, white blood cell count, hs-CRP, hemoglobin, fibrinogen, albumin levels, and Wanger grade 4 to 5 ratio, peripheral vascular lesions of the lower extremities, recent use of antibiotics and the healing time of ulcers in patients of diabetic foot recurrence and non-recurrent infections were statistically significant(t=6.003, 6.132, 3.144, 4.322, 4.513, 11.179, 7.164, χ2=4.269, 8.613, 25.083, 23.298, all P<0.05). Multivariate analysis showed that the independent risk factors for diabetic foot recurrence were peripheral vascular lesions of the lower extremities, recent use of antimicrobial agents, ulcer healing time more than 65 days(χ2=5.134, 4.807, 10.512, all P<0.05).@*Conclusion@#The results show that patients with ulcer healing time more than 65 days, vascular lesions around the lower extremities, and diabetic foot who recently used antibiotics have a higher risk of recurrent infections.Close observation should be made to take early precautionary measures based on the patients' own condition.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Risk factors Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Risk factors Language: Chinese Journal: Chinese Journal of Primary Medicine and Pharmacy Year: 2019 Type: Article