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A prospective study on the influence of metabolic syndrome on the risks of cardiovascular disease events and all-cause mortality for urban residents aged 40-79 years in Guiyang / 中华内分泌代谢杂志
Chinese Journal of Endocrinology and Metabolism ; (12): 743-746, 2019.
Article in Chinese | WPRIM | ID: wpr-797378
ABSTRACT
Objective@#To explore the influence of metabolic syndrome on the risks of cardiovascular disease (CVD) events and all-cause mortality.@*Methods@#In this prospective cohort study, urban residents aged 40-79 years in Guiyang were followed-up for three years. The end-points were CVD events and all-cause mortality. COX proportional hazards model were used for the corresponding hazard ratios (HRs) of CVD events and all-cause mortality. Metabolic syndrome was defined according to the 2005 International Diabetes Federation (IDF) criteria.@*Results@#A total of 7 313 subjects were included. 146 cases of CVD events and 80 cases of all-cause mortality were recorded. After adjusting for gender, age, smoking, alcohol consumption, and blood lipid levels, the metabolic syndrome increased the risks of CVD events and all-cause mortality. The HRs were 1.43 (P=0.037) and 1.25 (P=0.418), respectively. As compared metabolic syndrome with non-metabolic syndrome, an increased risk of CVD events was found. The HR was 1.43 (P=0.013). No significantly increased risk of all-cause mortality was found in subjects with metabolic syndrome.@*Conclusion@#The metabolic syndrome was associated with increased risk of CVD events and there was no significant increase in all-cause mortality. Metabolic syndrome is an important risk factor for CVD events.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Endocrinology and Metabolism Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Etiology study / Observational study / Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Endocrinology and Metabolism Year: 2019 Type: Article