Research progress in glycogen metabolism reprogramming in sepsis associated immune cells / 中华危重病急救医学
Chinese Critical Care Medicine
;
(12): 1167-1169, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-797541
ABSTRACT
Metabolic reprogramming is the response of cells to environmental changes, such as cell activation, proliferation and differentiation, which involves changes in metabolism-related enzymes, metabolites and metabolic pathways. Sepsis-associated immune cells undergo metabolic reprogramming in response to inflammatory signals, which not only provides biological energy and biosynthesis requirements, but also determines cell fate and function in a highly specific way. In this paper, the changes in glycolysis, tricarboxylic acid cycle, oxidative phosphorylation and other glucose metabolism pathways of macrophages, T lymphocytes, dendritic cells, neutrophils and other sepsis related immune cells are described, so as to provide feasibility for future research and metabolic therapy.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Critical Care Medicine
Year:
2019
Type:
Article
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