Analysis of whole-body bone scintigraphy and SPECT/CT imaging in osteoid osteoma / 中华核医学与分子影像杂志

ABSTRACT

Objective@#To analyze features of osteoid osteoma on whole-body bone scan (WBS) and SPECT/CT imaging.@*Methods@#From January 2010 to December 2018, 70 patients (50 males, 20 females, age 4-66 years) with osteoid osteoma confirmed by pathology were enrolled from the Affiliated Hospital of Southwest Medical University. All patients underwent WBS and SPECT/CT imaging and imaging features were retrospectively analyzed.@*Results@#A total of 70 lesions were found by WBS combined with SPECT/CT imaging, and 26 lesions (37.1%, 26/70) were found in the femur and 25 lesions (35.7%, 25/70) in the tibia. The radioactive ratio of target lesion to non-target lesion (T/NT) was 3.7±1.2 in 56 patients who underwent three-phase bone imaging. WBS showed that 48 lesions (68.6%, 48/70) were round (or nearly round), 21 lesions (30%, 21/70) were spindle-shaped, and 1 lesion (1.4%, 1/70) was irregular-shaped, while SPECT/CT imaging showed that 69 lesions (98.6%, 69/70) were round (or round) and 1 lesion (1.4%, 1/70) was irregular-shaped. The " double-density sign" was found in 48 lesions (68.6%, 48/70) by WBS and in 59 lesions (84.3%, 59/70) by SPECT/CT imaging. SPECT/CT imaging detected nidus in 59 lesions (84.3%, 59/70) and calcification or ossification (" target sign" ) in 27 lesions (38.6%, 27/70).@*Conclusion@#The typical features of osteoid osteoma on WBS and SPECT/CT imaging include " double density sign" , nidus and " target sign" , which contribute to the diagnosis of osteoid osteoma.