Anaesthesia effect of ropivacaine in different concentrations on intermuscular sulcus brachial plexus block under ultrasound guidance / 中国基层医药

ABSTRACT

Objective@#To explore the anesthetic effect of different concentrations of ropivacaine in intramuscular sulcus brachial plexus block under ultrasound guidance.@*Methods@#From April 2016 to April 2018, 120 patients with upper limb orthopedic surgery who received muscle under the ditch brachial plexus block guided by ultrasound in Jinhua Hospital of Traditional Chinese Medicine were randomly divided into group A (40 cases, application of 0.375% ropivacaine), group B (40 cases, application of 0.50% ropivacaine), group C (40 cases, application of 0.75% ropivacaine). The anesthetic effect, onset time of sensory block, onset time of motion block, duration of analgesia, recovery time of motion block, serum troponin level, creatine kinase isozyme level and incidence of adverse reactions in the three groups were compared.@*Results@#The excellent and good anesthesia rate of group A, group B and group C was 100.00%, and there was no statistically significant difference among the three groups (P>0.05). The onset time of sensory block[(5.29±1.32)min], the onset time of motion block[(7.42±1.36)min] in group C were shorter than those in group A[(9.32±1.52)min, (13.32±2.46)min] and group B[(7.89±1.63)min, (9.12±2.20)min](F=4.652, 6.365, all P<0.05). The analgesic duration in group C[(10.71±1.52)h] was longer than that in group A[(6.89±2.23)h] and group B[(8.69±2.12)h](F=5.120, P<0.05), but the recovery time of motion block in group C was longer than that in group A and group B (P<0.05). The serum troponin level and creatine kinase isozyme level at 24 h after injection in group C were significantly higher than those in group A and group B(P<0.05), and the serum troponin level and creatine kinase isozyme level in group B were significantly higher than those in group A (P<0.05). With the increase of concentration, the incidence of adverse reactions gradually increased, but there was no statistically significant difference among the three groups (P>0.05).@*Conclusion@#With the increase of ropivacaine concentration, the onset time of anesthesia is shorter and the analgesic time is longer, but the incidence of adverse reactions is also higher.In a comprehensive consideration, 0.50% ropivacaine can be applied to patients with intermuscular sulcus brachial plexus block under ultrasound guidance.