Research progress in immunoregulatory effects of adipose mesenchymal stem cells / 中华微生物学和免疫学杂志

ABSTRACT

Adipose derived mesenchymal stromal cells (ADSC) are pluripotent stem cells isolated from adipose tissue and have great application potential in regenerative medicine for their rich sources of derivation, relatively less trauma when sampling and few ethical problems. ADSC have preferable immunomodulatory capacity, and can regulate the immunologic functions of dendritic cells, macrophages, NK cells, NKT cells, B lymphocytes and T lymphocytes. In order to better understand the role of ADSC in immunoregulation, this paper systematically reviewed the immunomodulatory effects of ADSC on several representative immune cells.