Observation of clinical effect of photodynamic therapy on oral leukoplakia in elderly patients / 中华老年医学杂志
Chinese Journal of Geriatrics
;
(12): 1395-1397, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-800389
ABSTRACT
Objective@#To observe the clinical efficacy of photodynamic therapy on oral leukoplakia in elderly patients.@*Methods@#In this prospective study, fifteen elderly patients with oral leukoplakia were treated with 5-aminolevulinic acid-based photodynamic therapy(ALA-PDT). After 2 hours of dressing, patients were irradiated using a 635nm semiconductor laser with the power density of 300mW/cm2.Each lesion was irradiated for 6 minutes with energy density of 100J/cm2.The curative effect was evaluated and the adverse reactions were recorded based on the observation of lesion changes.@*Results@#Of the 15 lesions in 15 patients, 4 lesions were treated once, 3 lesions were treated twice.And 6 lesions were cured after three treatments, and 2 patients were cured after four treatments.The average treatment frequency was(2.4±1.1)treatment.The postoperative adverse reaction was pain.The average visual analogue scale was(2.2±0.8)scores after operation, and the duration of pain was(2.6±1.1)days after operation.There was no recurrence for 3 to 9 months after operation.No abnormalities of oral sensation and function were found in patients.@*Conclusions@#ALA-PDT is an effective method for the treatment of oral leukoplakia in elderly patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
Language:
Chinese
Journal:
Chinese Journal of Geriatrics
Year:
2019
Type:
Article
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