Research progress on reversion of multidrug resistance in tumor by cepharanthine / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 1407-1410, 2019.
Article
in Zh
| WPRIM
| ID: wpr-800658
Responsible library:
WPRO
ABSTRACT
This article reviews the related literature on the reversal of multi-drug resistance in tumors by cepharanthine, and summarizes the reversal effects and mechanisms of multi-drug resistance in different tumors such as leukemia, liver cancer, ovarian cancer, breast cancer, esophageal cancer and colon cancer. Its reversal effect on multi-drug resistance of tumors is the result of a multi-channel, multi-link combination. The main mechanism is to inhibit membrane transporter function, affect enzyme transfer system, inhibit anti-apoptotic pathway activation and anti-apoptotic protein expression.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
International Journal of Traditional Chinese Medicine
Year:
2019
Type:
Article