Progress of long non-coding RNA HOTAIR in leukemia / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 858-861, 2019.
Article
in Chinese
| WPRIM
| ID: wpr-800726
ABSTRACT
Long non-coding RNA (lncRNA) is a kind of regulatory RNA molecules with a length of more than 200nt, which can be involved in epigenetic modification of cells and gene expression by altering the chromatin status. HOTAIR is a kind of lncRNA, and some researches have found that HOTAIR may involved in the occurrence and development of leukemia, and it is obviously related to the diagnosis, treatment and prognosis of leukemia. This review summarizes the discovery, function, detection methods of HOTAIR and the latest research progress in leukemia, to provide new ideas for the diagnosis, individualized treatment and prognosis of leukemia.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2019
Type:
Article
Similar
MEDLINE
...
LILACS
LIS