Prevalence and influencing factors of carotid plaque in population at high-risk for cardiovascular disease in Jiangsu province / 中华流行病学杂志

ABSTRACT

Objective@#To understand the prevalence of carotid plaque (CP) in population at high-risk for cardiovascular disease (CVD) in Jiangsu province and identify related influencing factors.@*Methods@#Based on the China Patient-centered Evaluative Assessment of Cardiac Events Million Persons Project from 2015 to 2016, a total of 11 392 persons at high-risk for CVD were selected from six project areas in Jiangsu province for the questionnaire survey, physical measurement, laboratory test and bilateral ultrasound examination of carotid arteries. The prevalence of CP and influencing factors of abnormal carotid arteries, CP and plaque burden (CP≥2) were analyzed.@*Results@#Among the persons surveyed, 4 821 (42.3%) were males. The age of the persons surveyed was (59.4±8.9) years. There were 5 971 abnormal carotid arteries cases (52.4%), including 1 782 carotid intima-media thickness thickening cases (15.6%), 3 811 CP cases (33.5%) and 378 carotid stenosis cases (3.3%). Older age (OR=2.253, 95%CI 2.127-2.386), urban residence (OR=2.622, 95%CI 2.375-2.895), hypertension (OR=1.439, 95%CI 1.195-1.732), smoking (OR=1.441, 95%CI 1.259- 1.650), pulse pressure difference (OR=1.270, 95%CI 1.198-1.347), fasting plasma glucose (FPG) (OR=1.109, 95%CI 1.059-1.161) and LDL-C/HDL-C (OR=1.225, 95%CI 1.164-1.288) were possible risk factors of CP in population at high risk for CVD. Being women (OR=0.558, 95%CI 0.494-0.630), high BMI (OR=0.948, 95%CI 0.904-0.994), higher levels of education (OR=0.708, 95%CI 0.531-0.945), and higher annual household income (OR=0.773, 95%CI 0.669-0.894) were the possible protective factors.@*Conclusions@#Over half of the population at high-risk for CVD in Jiangsu showed abnormal carotid arteries. High blood pressure, high blood glucose, high blood lipids and smoking were the main factors that could be changed.