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Research progress of exosomes in the occurrence and development of gastric cancer / 中国肿瘤生物治疗杂志
Chinese Journal of Cancer Biotherapy ; (6): 1154-1158, 2018.
Article in Chinese | WPRIM | ID: wpr-801660
ABSTRACT
@#外泌体通过胞内体内陷形成多泡体再与质膜融合后释放,其内含有蛋白质、脂质、核酸等生物活性物质。外泌体通过 与受体细胞融合,将其内含的生物活性物质作为信号分子传递给受体细胞,从而介导细胞间信号交流。胃癌细胞分泌大量的外 泌体,可影响周围细胞的功能,在调控胃癌的生物学行为中发挥重要作用。外泌体在胃癌相关研究中取得较多新进展,包括对胃 癌的生长、转移、免疫逃避、耐药性等生物学行为的影响及相关机制,以及作为药物载体在胃癌靶向治疗中的临床应用。

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Cancer Biotherapy Year: 2018 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Cancer Biotherapy Year: 2018 Type: Article