Prevalence of degenerative knee osteoarthritis and its correlation with osteoporosis / 中华骨科杂志

ABSTRACT

Objective@#To investigate the prevalence of degenerative knee osteoarthritis and the relationship between osteoporosis and knee osteoarthritis.@*Methods@#A community-based cross-sectional study was conducted and stratified sampling method was used to select the sample. The permanent residents over 18 years old in Beijing were selected, and self-developed questionnaires were used by face-to-face interview including the disease condition and possible relative factors. The effect of osteoporosis on knee osteoarthritis was analyzed after controlling the effect of gender, age, BMI, waist-hip ratio, education level, nature of work, intensity of work, physical exercise by the Logistic regression model.@*Results@#Among the 783 subjects, 53 cases of knee degenerative osteoarthritis were found, with the prevalence rate was 6.77% and the prevalence rate of 95%CI was 5.01%, 8.53%. The prevalence rates of <45 years old group, 45-59 year-old group and ≥60-year-old group were 2.54%, 7.02% and 16.67% respectively, and the difference was statistically significant (χ2=36.284, P=0.000). After controlling the other factors, osteoporosis had an independent effect on knee osteoarthritis with OR value of 3.56 (95%CI 1.76, 7.18).@*Conclusion@#The older the age, the higher the prevalence of degenerative knee arthritis, and there is a correlation between osteoporosis and degenerative knee arthritis.