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Mesothelin and immunotherapy for pancreatic cancer / 中华内分泌外科杂志
Chinese Journal of Endocrine Surgery ; (6): 510-513, 2019.
Article in Chinese | WPRIM | ID: wpr-805320
ABSTRACT
As one of the most lethal malignancies, pancreatic cancer and its therapy remains a big problem all around the world. With the few candidates for surgery and the poor outcome for chemotherapy, the immunotherapy becomes one important direction. Mesothelin, a membrane protein, expresses at low levels in normal tissues, but is re-expressed at a high frequency in pancreatic cancer, which makes mesothelin an ideal target for immunotherapy.This review summarizes the progression of mesothein-targeted immunotherapy for pancreatic cancer.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Endocrine Surgery Year: 2019 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Endocrine Surgery Year: 2019 Type: Article