Molecular characteristics of norovirus in 4 outbreaks of gastroenteritis in Heilongjiang province in 2016 / 中华实验和临床病毒学杂志

ABSTRACT

Objective@#To study the molecular characteristics of norovirus in 4 outbreaks of gastroenteritis in Heilongjiang province in 2016.@*Methods@#Fecal specimens of patients were collected from 4 outbreaks of acute viral gastroenteritis. Real-time PCR was performed to identify the infection with Norovirus (NoV). The NoV genes were amplified and sequenced for the positive samples, followed by performing phylogenetic analysis.@*Results@#There were total 4 outbreaks of viral gastroenteritis caused by NoV. A total of 102 stool specimens were obtained from cases with acute gastroenteritis. NoV was detected in 35 cases including 14 strains of genogroup I NoV and 21 strains of genogroup II NoV. Six genotypes including GII.2, GII.17, GII.Pe, GII.P12/GII.3, GI.6, GI.Pd/GI.3 were detected.@*Conclusions@#NoV was the pathogen causing the gastroenteritis outbreaks in Heilongjiang province, and multigenotype NoV co-circulated in Heilongjiang province.