A Case of Central Diabetes Insipidus with Growth Hormone Deficiency and Loss of Hyperintense Signal in the Posterior Lobe / 대한소아내분비학회지
Journal of Korean Society of Pediatric Endocrinology
;
: 221-224, 2002.
Article
in Korean
| WPRIM
| ID: wpr-80683
ABSTRACT
Central diabetes insipidus is a rare disorder that can result as a consequence of diverse etiologies, including malformations, autoimmune, infiltrative(e.g. neoplastic or histiocytosis) or traumatic processes, as well as mutations in the gene encoding arginine vasopressin. Idiopathic central diabetes insipidus is a diagnosis of exclusion, one that has been made less frequently through the decades. Idiopathic central diabetes insipidus in children and adolescent requires a frequent follow-up regimen using serial brain MRI and CSF examinations especially if an isolated pituitary stalk thickening or loss of a hyperintense signal in the posterior lobe is observed. Also, so-called "idiopathic" central diabetes insipidus warrants close follow-up to determine the etiology, especially if anterior pituitary hormone deficiencies are detected. We report a case of idiopathic central diabetes insipidus with growh hormone deficiency and loss of a hyperintense signal in the posterior lobe. He is a 13 years old. We are scheduled to follow-up with serial contrast enhanced brain MRI and CSF evaluation for the early detection of an evolving occult hypothalamic-stalk lesion.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pituitary Gland
/
Brain
/
Arginine Vasopressin
/
Growth Hormone
/
Magnetic Resonance Imaging
/
Follow-Up Studies
/
Diabetes Insipidus, Neurogenic
/
Diagnosis
Type of study:
Diagnostic study
/
Observational study
/
Prognostic study
/
Screening study
Limits:
Adolescent
/
Child
/
Humans
Language:
Korean
Journal:
Journal of Korean Society of Pediatric Endocrinology
Year:
2002
Type:
Article
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