Exosomes: new markers for tumor diagnosis / 中华检验医学杂志

ABSTRACT

Exosomes are nanoscale extracellular vesicles, which range in size from 30 to 150 nm, and are released under physiological and pathological conditions. The content of exosomes reflects the origin and function of cells. As a form of intercellular vesicular transport, exosome-mediated intercellular communication participates in a variety of physiological and pathological processes. The information transmission mediated by exosomes is associated with pathophysiological status and plays an important role in the pathogenesis of cancer. This review summarizes the research progress of exosomes, including the origin and biological functions, the detection methods, the diagnosis and treatment of tumor.(Chin J Lab Med, 2018, 41: 491-495)