Research progress of beta3-adrenergic receptor in heart / 中国小儿急救医学
Chinese Pediatric Emergency Medicine
;
(12): 530-535, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-807014
ABSTRACT
The expression of beta3-adrenergic receptor(β3-AR) is very low in the physiological state of the heart, but increases in the pathological state of heart failure.Due to the negative inotropic effect when stimulating β3-AR, the early researchers believed that the increase of β3-AR in the pathological state would aggravate the cardiac function, but the later researches of beta3-AR on heart failure found a contrary conclusion.More and more evidence suggests that beta3-AR may play a useful role in the cardiovascular system, which making beta3-AR to be a new target for the treatment of cardiovascular disease.This article reviewed the progress of the above researches.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pediatric Emergency Medicine
Year:
2018
Type:
Article
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