Two Cases of Heparin-Induced Thrombocytopenia Diagnosed by Particle Gel Immunoassay / 대한진단검사의학회지
The Korean Journal of Laboratory Medicine
;
: 334-337, 2006.
Article
in Korean
| WPRIM
| ID: wpr-80719
ABSTRACT
Heparin-induced thrombocytopenia (HIT) is a serious complication of heparin therapy. It represents initially as thrombocytopenia and is associated with venous or arterial thrombosis. It has been reported that platelet factor 4/heparin complex antibody plays an important role in the pathogenesis of HIT. Patients on hemodialysis have a high risk of developing HIT because heparin is administrated in hemodialysis as anticoagulant. Thrombocytopenia usually occurs 5 to 10 days after the onset of administration, but occasionally, it may occur rapidly in patients who have preformed antibodies from recent heparin use. We report here 2 cases of HIT with platelet factor 4-heparin reactive antibody in hemodialysis patients.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Thrombocytopenia
/
Thrombosis
/
Blood Platelets
/
Immunoassay
/
Heparin
/
Renal Dialysis
/
Antibodies
Type of study:
Diagnostic study
Limits:
Humans
Language:
Korean
Journal:
The Korean Journal of Laboratory Medicine
Year:
2006
Type:
Article
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