Study on the quality control of Zicao ointment / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
;
(6): 738-741, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-807288
ABSTRACT
Objective@#Study on the improvement of quality standard for Zicao ointment.@*Methods@#The content of shikonin and β,β’-dimethylacrylshikonin was determined by high performance liquid chromatogram (HPLC). The column was Inertsil ODS-3 C18 column (4.6 mm×250 mm, 5 μm). The mobile phase comprising of acetonitrile-0.05% formic acid solution (7030). The flow rate was 1.0 ml/min, the detection wavelength was 275 nm, and the column temperature was 25 ℃.@*Results@#The linear range of shikonin and β,β’-dimethylacrylshikonin were 0.04-0.81 μg (r=0.999 5) and 0.41-10.36 μg (r=0.999 2). The average recovery were 103.32% and 101.80%, the RSD were 1.96% and 2.11%.@*Conclusions@#The method is simple, accurate and sensitive to control the quality of Zicao ointment.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Traditional Chinese Medicine
Year:
2018
Type:
Article
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