Progress of heart and neural crest derivatives-expressed transcript 2 gene in endometrial carcinoma / 肿瘤研究与临床
Cancer Research and Clinic
;
(6): 572-576, 2018.
Article
in Chinese
| WPRIM
| ID: wpr-807321
ABSTRACT
The neural crest derivatives expressed 2 (Hand2) is one of the most important transcription factors in the basic helix-hoop-helix (bHLH) protein family. It is expressed in a variety of organ tissues, which regulates the differentiation of multiple stem cells into end cells. Endometrial carcinoma is one of the three major reproductive system tumors that pose a serious threat to women's health, and its pathogenesis is not yet clear. Recent studies have shown that the Hand2 gene is a kind of methylation hotspot in endometrial carcinoma, which is closely related to the development of endometrial carcinoma. This review describes the progress of Hand2 gene in endometrial cancer.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Cancer Research and Clinic
Year:
2018
Type:
Article
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