Analysis of etiology and pregnancy outcome in 120 cases with fetal intrauterine growth restriction / 中国基层医药

ABSTRACT

Objective@#To explore the etiology and pregnancy outcome of fetal intrauterine growth restriction(FGR).@*Methods@#120 cases of FGR pregnant women were selected as the research subjects(FGR group). And 120 healthy pregnant women who were successfully delivered during the same period were selected as the control group.The medical records and pregnancy outcomes in the two groups were analyzed and compared.@*Results@#There was no statistically significant difference in age between the FGR group and the control group (t=1.0978, P>0.05). In the FGR group, the proportions of pregnant women who came from the countryside, without prenatal examination and the choice of cesarean section were significantly higher than those in the control group, and the differences between the two groups were statistically significant(χ2=8.832, 4.842, 7.466, 4.843, all P<0.05). The proportions of pregnancy induced hypertension, heart lung disease, premature rupture of membranes, anemia, oligohydramnios, abnormal umbilical cord, placental abnormalities intrauterine distress and meconium infection and twin pregnant women in the FGR group were significantly higher than those in the control group(χ2=12.810, 4.655, 6.666, 12.860, 16.335, 6.587, 4.629, 6.696, 7.924, 8.038, all P<0.05), these factors were the causative factors of FGR.The neonatal quality and gestational age in the FGR group were (2 134.32±322.17)g and (35.74±2.12)weeks, respectively, which were significantly lower than those in the control group[(2 793.83±427.64)g, (38.23±2.75)weeks](t=13.493, 7.855, all P<0.05). The incidence rates of neonatal morbidity, neonatal asphyxia and neonatal death in the FGR group were 15.00%, 3.33% and 4.17%, respectively, which were significantly higher than 3.33%, 1.67%, 0.00% in the control group(χ2=9.808, 4.668, 5.106, all P<0.05).@*Conclusion@#The incidence of FGR is associated with pregnancy induced hypertension, heart lung disease, premature rupture of membranes, anemia, oligohydramnios, abnormal umbilical cord, placental abnormalities intrauterine distress, meconium infection and twins.FGR should be promptly diagnosed and treated in the clinical, can terminate pregnancy when necessary, as soon as possible to improve the adverse pregnancy outcome.Improving the adverse pregnancy outcomes as much as possible can achieve the purpose of eugenics.