Comparison of effects of breast conserving surgery and modified radical mastectomy for early breast cancer / 中国基层医药

ABSTRACT

Objective@#To compare the clinical effect of breast conserving surgery and modified radical mastectomy for early breast cancer.@*Methods@#The clinical data of 100 patients with early breast cancer who received surgical treatment and completed 5 years of follow-up were retrospectively analyzed.According to the operation mode, the patients were divided into the conservative group(47 cases) and radical group (53 cases). The patients underwent breast conserving surgery, surgical treatment of modified radical mastectomy respectively.The objective response rate, the effect of aesthetic breast appearance, postoperative 5 years survival rate, local recurrence rate, distant metastasis rate, survival quality were compared between the two groups.@*Results@#The objective remission rate of the conservative group and radical group was 82.98%, 86.79%, respectively, the difference was not statistically significant (χ2=0.284, P>0.05). The aesthetic good rate of the conservative group was 91.49%, which was higher than 0.00% of the radical group (χ2=85.609, P<0.01). The 5-year survival rate, local recurrence rate, distant metastasis rate of the conservative group were 95.74%, 6.38%, 4.26%, respectively, which of the radical group were 96.23%, 1.89%, 3.77%, respectively, the differences between the two groups were not statistically significant (χ2=0.015, 1.311, 0.015, all P>0.05). The scores of physical health, mental health, social function, quality of life score of material life of the conservative group were (79.37±8.19)points, (83.56±11.21)points, (81.48±10.95)points, (83.19±11.34)points, respectively, which were significantly higher than those of the radical group [(71.58±6.23)points, (71.87±8.65)points, (70.62±9.17)points, (71.76±8.79)points](t=5.388, 5.873, 5.396, 5.666, all P<0.05).@*Conclusion@#For patients with early breast cancer, the clinical effect of breast conserving surgery is similar with the modified radical mastectomy, it can effectively improve the breast appearance and the quality of life of patients.