Analysis of hepatitis B infection and immune status of the first-year students in a university / 中华实验和临床病毒学杂志

ABSTRACT

Objective@#To study the hepatitis B infection and immune status of the first-year students in a university and to provide evidence for the hepatitis B prevention in the university.@*Methods@#Subjects were the first-year students in a university; questionnaires were distributed. Enzyme-linked immunosorbent assay (ELISA) was adopted to test HBsAg and anti-HBs in serum.@*Results@#The hepatitis B vaccine inoculation rate was 80.8% among 728 subjects, the inoculation rate of urban students was higher than that of rural students (P<0.005). The HBsAg positive rate was 3.4%, no significant difference was found among students in cities and countryside. The anti-HBs positive rate was 65.2%, the positive rate of urban students was higher than that of rural students (P<0.005). The positive rate of anti-HBs in students with hepatitis B vaccination history was significantly higher than that of students without history of vaccination against hepatitis B. No significant differences were found between male and female students for all the groups.@*Conclusions@#By combining the condition of inoculation history of the first-year students in the university and the testresult of HBsAg and anti-HBs, it is necessary to strengthen vaccination against hepatitis B. The prevention of hepatitis B and inoculation of hepatitis B vaccine in the countryside should be strengthened.