Leukocytosis Prevalence according to Smoking among Men
Journal of the Korean Academy of Family Medicine
;
: 762-767, 2007.
Article
in Korean
| WPRIM
| ID: wpr-80941
ABSTRACT
BACKGROUND:
Cigarette smoke exposure accelerates the release of leukocytes from the bone marrow, which is postulated to be mediated by inflammatory cytokines and haematopoietic growth factors released from the lung.METHODS:
The study population consisted of 2,270 healthy men above 20 years of age who had visited a health promotion center in a university hospital from January 2005 to December 2005. Baseline health check, self- reported cigarette smoking habit and blood sample were evaluated. The mean count of leukocytes and the leukocytosis prevalence according to smoking amounts were investigated.RESULTS:
As the daily smoking amount was increased and as pack years smoked was increased, the mean total WBC count values and the prevalence of leukocytosis were higher (P=0.000). The odds ratio (OR) for leukocytosis according to daily smoking amount compared to no smokers was 1.98 (95% confidence interval (CI) 1.01~3.88) in those who smoked 1/2~1 pack per day and 4.17 (95% CI 1.83~9.48) in those who smoked more than 1 pack per day. The OR for leukocytosis according to smoking pack years compared to no smokers was 2.58 (95% CI 1.22~5.42) in those who smoked 20~30 pack years, 3.31 (95% CI 1.38~7.93) in those who smoked 30~40 pack years and 5.17 (95% CI 2.00~13.32) in those who smoked more than 40 pack years.CONCLUSION:
The mean count of leukocytes and the prevalence of leukocytosis were higher in current smokers than no smokers and ex-smokers.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Smoke
/
Bone Marrow
/
Smoking
/
Odds Ratio
/
Prevalence
/
Cytokines
/
Intercellular Signaling Peptides and Proteins
/
Tobacco Products
/
Health Promotion
/
Leukocyte Count
Type of study:
Etiology study
/
Prevalence study
/
Risk factors
Limits:
Humans
/
Male
Language:
Korean
Journal:
Journal of the Korean Academy of Family Medicine
Year:
2007
Type:
Article
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