Progress in research of effect of pregnancy complicated with hepatitis B virus infection on maternal and infant safety / 中华流行病学杂志

ABSTRACT

Hepatitis B virus (HBV) infection is one of the important public health problems. In order to eliminate the threat of viral hepatitis to public health, World Health Organization has proposed to achieve the goal of reducing the HBsAg positive rate in children to 0.1% by 2030. There are regional differences in HBsAg positive rates among pregnant women worldwide, from 0.6% in areas with low prevalence to 20% in areas with high prevalence. The positive rate of HBsAg in pregnant women in China is higher than global average. In recent years, several studies have found that HBV infection in pregnancy not only increase the risk of mother-to-child transmission, but also adversely affect the health of pregnant women and their children. Therefore, this paper summarizes the progress in research both at home and abroad in terms of HBsAg positive rate in pregnant women and the influence of pregnancy complicated with HBV infection on pregnant women and perinatal infants in order to explore the effect of pregnancy complicated with HBV infection on maternal and infant safety.